We present you all the best options available in S11. The runes listed below on the page showed effectiveness for this character in 2021 year, because they can unlock most of his strengths and also neutralize the maximum possible amount of weaknesses.
The list includes all the options that have any value nowadays. This will allow to flexibly adapt to your opponent in the role and team compositions in general when playing the champion Zoe (for example, if you need to be really aggressive).
All the optimal builds for mid lane in LoL
Plus opportunities for early skirmishes
Primary path
Domination
Electrocute
Taste of Blood
Secondary
Inspiration
Biscuit Delivery
Time Warp Tonic
+ 2 others and statistics slots
Read complete descriptionElectrocute together with all the additional runes from Domination path will make Zoe much stronger while playing mid lane in season 11 League of Legends.
The secondary path is Inspiration. Biscuit Delivery will provide health and mana on the lane, as well as increase the maximum amount of the latter. Time... read more
Plus additional increase of the CDR
Primary path
Domination
Electrocute
Taste of Blood
Secondary
Sorcery
Nimbus Cloak
Transcendence
+ 2 others and statistics slots
Read complete descriptionElectrocute together with all the additional runes from Domination path will make Zoe much stronger while playing mid lane in season 11 League of Legends.
The secondary path is Sorcery. Nimbus Cloak will give the champion a good movement speed boost after using a summoner spell. Transcendence is perfect... read more
Plus opportunities for early skirmishes
Primary path
Sorcery
Summon Aery
Nimbus Cloak
Secondary
Inspiration
Biscuit Delivery
Time Warp Tonic
+ 2 others and statistics slots
Read complete descriptionSummon Aery together with all the additional runes from Sorcery path will make Zoe much stronger while playing mid lane in season 11 League of Legends.
The secondary path is Inspiration. Biscuit Delivery will provide health and mana on the lane, as well as increase the maximum amount of the latter. Time... read more
Plus restoration of health in the fight
Primary path
Sorcery
Summon Aery
Nimbus Cloak
Secondary
Domination
Taste of Blood
Ravenous Hunter
+ 2 others and statistics slots
Read complete descriptionSummon Aery together with all the additional runes from Sorcery path will make Zoe much stronger while playing mid lane in season 11 League of Legends.
The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more
Plus additional increase of the CDR
Primary path
Inspiration
Unsealed Spellbook
Magical Footwear
Secondary
Sorcery
Nimbus Cloak
Transcendence
+ 2 others and statistics slots
Read complete descriptionUnsealed Spellbook together with all the additional runes from Inspiration path will make Zoe much stronger while playing mid lane in season 11 League of Legends.
The secondary path is Sorcery. Nimbus Cloak will give the champion a good movement speed boost after using a summoner spell. Transcendence is perfect... read more
All the optimal builds for the ARAM in LoL
Plus more mana and threat to enemies
Primary path
Domination
Dark Harvest
Taste of Blood
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionDark Harvest together with all the additional runes from Domination path will make Zoe much stronger while playing the ARAM in season 11 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus additional increase of the CDR
Primary path
Domination
Dark Harvest
Taste of Blood
Secondary
Sorcery
Nimbus Cloak
Transcendence
+ 2 others and statistics slots
Read complete descriptionDark Harvest together with all the additional runes from Domination path will make Zoe much stronger while playing the ARAM in season 11 League of Legends.
The secondary path is Sorcery. Nimbus Cloak will give the champion a good movement speed boost after using a summoner spell. Transcendence is perfect... read more
Plus more mana and threat to enemies
Primary path
Sorcery
Arcane Comet
Nimbus Cloak
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Zoe much stronger while playing the ARAM in season 11 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus restoration of health in the fight
Primary path
Sorcery
Arcane Comet
Nimbus Cloak
Secondary
Domination
Taste of Blood
Ravenous Hunter
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Zoe much stronger while playing the ARAM in season 11 League of Legends.
The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more