The complete list:

Runes for Vayne

Vayne runes for ADC №2 in League of Legends S10 (2020)

Introducing the option that will provide the champion lots of healing in lane plus saving and enhancing early game. A detailed description of everything that is contained in it will allow you to fully understand its strengths and weaknesses.

Below on this page you will see what you need to take - the main branch, additional, as well as slots with statistics. You can also familiarize yourself with the benefits of option. Keep in mind that it may not be suitable for all situations.


A detailed description of this build for Vayne in LoL

You can get detailed information about all runes, as well as find out any of their numerical values, at the stage of setting them up in the League of Legends client using the option in the lower left corner.

PositionWhat to choose
Primary pathPrecision
KeystonePress the Attack
AdditionalTriumph, Legend: Alacrity, Coup de Grace
Secondary pathSorcery
Slots in itNimbus Cloak, Gathering Storm
Stats10% attack speed, 9 adaptive force, 6 armor

The main path for the champion Vayne is Precision. In it, you will need to choose one keystone rune, as well as three additional ones with less influence.

Press the Attack is used as the keystone rune. With its help Vayne will increase the damage done on one target. This rune not only inflicts additional damage to the enemy after three auto attacks, but also weakens the enemy, increasing all subsequent damage to it.

Triumph is a very powerful rune, giving healing and additional gold when participating in the killing of an enemy champion. Legend: Alacrity will provide a decent amount of attack speed. Coup de Grace will allow you to do more damage to enemies with low health.

The secondary path is Sorcery. Here you need to choose two additional runes for Vayne.

Nimbus Cloak will give the champion a good movement speed boost after using a summoner spell. Gathering Storm will allow you to take up the enemy in long games thanks to a large amount of attack damage or ability power.