The complete list:

Support (view best option)

Mid lane (view best option)

ARAM 5v5 (view best option)

Runes for Seraphine in League of Legends season 11

We present you all the best options available in S11. The runes listed below on the page showed effectiveness for this character in 2021 year, because they can unlock most of his strengths and also neutralize the maximum possible amount of weaknesses.

The list includes all the options that have any value nowadays. This will allow to flexibly adapt to your opponent in the role and team compositions in general when playing the champion Seraphine (for example, if you need to be really aggressive).

Please, choose the position you need

Support

Mid lane

ARAM 5v5


Seraphine runes for sup in League of Legends

All the optimal builds for support in LoL

Seraphine runes: sup №1 in LoL S11

Protecting allies with shields

Plus resource recovery and CDR

Primary path

Resolve

Guardian

Shield Bash

Secondary

Inspiration

Biscuit Delivery

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Guardian together with all the additional runes from Resolve path will make Seraphine much stronger while playing support in League of Legends season 11.

The secondary path is Inspiration. Biscuit Delivery will provide health and mana on the lane, as well as increase the maximum amount of the latter. Cosmic... read more

Seraphine runes: sup №2 in LoL S11

Protecting allies with shields

Plus more mana and increased CDR

Primary path

Resolve

Guardian

Shield Bash

Secondary

Sorcery

Manaflow Band

Transcendence

+ 2 others and statistics slots

Read complete description

Runes of the Resolve path are well suited for support in League of Legends season 11. Guardian is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more

Seraphine runes: sup №3 in LoL S11

Abilities and attacks damage

Plus resource recovery and CDR

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Inspiration

Biscuit Delivery

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Summon Aery together with all the additional runes from Sorcery path will make Seraphine much stronger while playing support in League of Legends season 11.

The secondary path is Inspiration. Biscuit Delivery will provide health and mana on the lane, as well as increase the maximum amount of the latter. Cosmic... read more

Seraphine runes: sup №4 in LoL S11

Abilities and attacks damage

Plus more survivability the whole game

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Resolve

Bone Plating

Revitalize

+ 2 others and statistics slots

Read complete description

Runes of the Sorcery path are well suited for support in League of Legends season 11. Summon Aery is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Resolve. Bone Plating will reduce the incoming damage of the first enemy attacks and skills, which will make you less vulnerable... read more

Seraphine runes: sup №5 in LoL S11

Abilities and attacks damage

Plus significant CDR of the ultimate

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Domination

Zombie Ward

Ultimate Hunter

+ 2 others and statistics slots

Read complete description

Summon Aery together with all the additional runes from Sorcery path will make Seraphine much stronger while playing support in League of Legends season 11.

The secondary path is Domination. Zombie Ward shows itself perfectly when constantly cleaning enemy wards, since it creates your own in their place, and... read more

Seraphine runes: sup №6 in LoL S11

Harassing enemy with skills

Plus resource recovery and CDR

Primary path

Sorcery

Arcane Comet

Manaflow Band

Secondary

Inspiration

Biscuit Delivery

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Runes of the Sorcery path are well suited for support in League of Legends season 11. Arcane Comet is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Inspiration. Biscuit Delivery will provide health and mana on the lane, as well as increase the maximum amount of the latter. Cosmic... read more

Seraphine runes: sup №7 in LoL S11

Harassing enemy with skills

Plus significant CDR of the ultimate

Primary path

Sorcery

Arcane Comet

Manaflow Band

Secondary

Domination

Zombie Ward

Ultimate Hunter

+ 2 others and statistics slots

Read complete description

Arcane Comet together with all the additional runes from Sorcery path will make Seraphine much stronger while playing support in League of Legends season 11.

The secondary path is Domination. Zombie Ward shows itself perfectly when constantly cleaning enemy wards, since it creates your own in their place, and... read more

Seraphine runes: sup №8 in LoL S11

The maximum burst damage

Plus resource recovery and CDR

Primary path

Domination

Electrocute

Cheap Shot

Secondary

Inspiration

Biscuit Delivery

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Runes of the Domination path are well suited for support in League of Legends season 11. Electrocute is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Inspiration. Biscuit Delivery will provide health and mana on the lane, as well as increase the maximum amount of the latter. Cosmic... read more


Seraphine runes for mid in League of Legends

All the optimal builds for mid lane in LoL

Seraphine runes: mid №1 in LoL S11

Abilities and attacks damage

Plus saving and enhancing early game

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Inspiration

Magical Footwear

Biscuit Delivery

+ 2 others and statistics slots

Read complete description

Summon Aery together with all the additional runes from Sorcery path will make Seraphine much stronger while playing mid lane in League of Legends season 11.

The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Biscuit Delivery will provide... read more

Seraphine runes: mid №2 in LoL S11

Abilities and attacks damage

Plus true damage and CDR of ultimate

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Domination

Cheap Shot

Ultimate Hunter

+ 2 others and statistics slots

Read complete description

Runes of the Sorcery path are well suited for mid lane in League of Legends season 11. Summon Aery is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Domination. Cheap Shot will serve as a constant source of additional damage to enemies after applying any control to them. Ultimate... read more

Seraphine runes: mid №3 in LoL S11

Abilities and attacks damage

Plus more mana and threat to enemies

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Summon Aery together with all the additional runes from Sorcery path will make Seraphine much stronger while playing mid lane in League of Legends season 11.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Seraphine runes: mid №4 in LoL S11

Lots of slows for your enemies

Plus huge amount of CDR for active items

Primary path

Inspiration

Glacial Augment

Magical Footwear

Secondary

Domination

Cheap Shot

Ingenious Hunter

+ 2 others and statistics slots

Read complete description

Runes of the Inspiration path are well suited for mid lane in League of Legends season 11. Glacial Augment is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Domination. Cheap Shot will serve as a constant source of additional damage to enemies after applying any control to them. Ingenious... read more

Seraphine runes: mid №5 in LoL S11

The maximum burst damage

Plus more mana and increased CDR

Primary path

Domination

Electrocute

Cheap Shot

Secondary

Sorcery

Manaflow Band

Transcendence

+ 2 others and statistics slots

Read complete description

Electrocute together with all the additional runes from Domination path will make Seraphine much stronger while playing mid lane in League of Legends season 11.

The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more

Seraphine runes: mid №6 in LoL S11

Continuous damage increase

Plus more mana and increased CDR

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Sorcery

Manaflow Band

Transcendence

+ 2 others and statistics slots

Read complete description

Runes of the Domination path are well suited for mid lane in League of Legends season 11. Dark Harvest is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more

Seraphine runes: mid №7 in LoL S11

Harassing enemy with skills

Plus saving and enhancing early game

Primary path

Sorcery

Arcane Comet

Manaflow Band

Secondary

Inspiration

Magical Footwear

Biscuit Delivery

+ 2 others and statistics slots

Read complete description

Arcane Comet together with all the additional runes from Sorcery path will make Seraphine much stronger while playing mid lane in League of Legends season 11.

The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Biscuit Delivery will provide... read more

Seraphine runes: mid №8 in LoL S11

Harassing enemy with skills

Plus true damage and CDR of ultimate

Primary path

Sorcery

Arcane Comet

Manaflow Band

Secondary

Domination

Cheap Shot

Ultimate Hunter

+ 2 others and statistics slots

Read complete description

Runes of the Sorcery path are well suited for mid lane in League of Legends season 11. Arcane Comet is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Domination. Cheap Shot will serve as a constant source of additional damage to enemies after applying any control to them. Ultimate... read more


Seraphine runes for ARAM in League of Legends

All the optimal builds for the ARAM in LoL

Seraphine runes: ARAM №1 in LoL S11

Abilities and attacks damage

Plus more mana and threat to enemies

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Summon Aery together with all the additional runes from Sorcery path will make Seraphine much stronger while playing the ARAM in League of Legends season 11.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Seraphine runes: ARAM №2 in LoL S11

Abilities and attacks damage

Plus true damage and CDR of ultimate

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Domination

Cheap Shot

Ultimate Hunter

+ 2 others and statistics slots

Read complete description

Runes of the Sorcery path are well suited for the ARAM in League of Legends season 11. Summon Aery is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Domination. Cheap Shot will serve as a constant source of additional damage to enemies after applying any control to them. Ultimate... read more

Seraphine runes: ARAM №3 in LoL S11

Continuous damage increase

Plus more mana and increased CDR

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Sorcery

Manaflow Band

Transcendence

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Seraphine much stronger while playing the ARAM in League of Legends season 11.

The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more

Seraphine runes: ARAM №4 in LoL S11

Harassing enemy with skills

Plus restoration of health in the fight

Primary path

Sorcery

Arcane Comet

Manaflow Band

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Runes of the Sorcery path are well suited for the ARAM in League of Legends season 11. Arcane Comet is especially worth mentioning as it gives Seraphine a big advantage.

Next you should take Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more