The complete list:

In jungle

Mid lane

Bot lane

ARAM 5v5

Runes for Karthus in League of Legends season 11

We present you all the best options available in S11. The runes listed below on the page showed effectiveness for this character in 2021 year, because they can unlock most of his strengths and also neutralize the maximum possible amount of weaknesses.

The list includes all the options that have any value nowadays. This will allow to flexibly adapt to your opponent in the role and team compositions in general when playing the champion Karthus (for example, if you need to be really aggressive).

Please, choose the position you need

In jungle

Mid lane

Bot lane

ARAM 5v5


Karthus runes for jng in League of Legends

All the optimal builds for the jungle in LoL

Karthus runes: jng №1 in LoL S11

Continuous damage increase

Plus more mana and threat to enemies

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing the jungle in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Karthus runes: jng №2 in LoL S11

Continuous damage increase

Plus saving in the early game and CDR

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Inspiration

Magical Footwear

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing the jungle in season 11 League of Legends.

The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Cosmic Insight allows you to get... read more

Karthus runes: jng №3 in LoL S11

Continuous damage increase

Plus maximum increase in strength

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Sorcery

Absolute Focus

Gathering Storm

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing the jungle in season 11 League of Legends.

The secondary path is Sorcery. Absolute Focus will maximize the advantage over the opponent thanks to additional stats when your level of health is... read more

Karthus runes: jng №4 in LoL S11

Damage and lots of healing

Plus maximum increase in strength

Primary path

Precision

Conqueror

Triumph

Secondary

Sorcery

Absolute Focus

Gathering Storm

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Karthus much stronger while playing the jungle in season 11 League of Legends.

The secondary path is Sorcery. Absolute Focus will maximize the advantage over the opponent thanks to additional stats when your level of health is... read more

Karthus runes: jng №5 in LoL S11

Damage and lots of healing

Plus saving in the early game and CDR

Primary path

Precision

Conqueror

Triumph

Secondary

Inspiration

Magical Footwear

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Karthus much stronger while playing the jungle in season 11 League of Legends.

The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Cosmic Insight allows you to get... read more

Karthus runes: jng №6 in LoL S11

Impressive amount of mobility

Plus more mana and threat to enemies

Primary path

Sorcery

Phase Rush

Nimbus Cloak

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Karthus much stronger while playing the jungle in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more


Karthus runes for mid in League of Legends

All the optimal builds for mid lane in LoL

Karthus runes: mid №1 in LoL S11

Continuous damage increase

Plus more mana and threat to enemies

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Karthus runes: mid №2 in LoL S11

Continuous damage increase

Plus maximum increase in strength

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Sorcery

Transcendence

Gathering Storm

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Sorcery. Transcendence is perfect for champions who need to reduce cooldowns. Gathering Storm will allow you to take up the enemy... read more

Karthus runes: mid №3 in LoL S11

Continuous damage increase

Plus saving in the early game and CDR

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Inspiration

Magical Footwear

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Cosmic Insight allows you to get... read more

Karthus runes: mid №4 in LoL S11

Abilities and attacks damage

Plus more mana and threat to enemies

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Summon Aery together with all the additional runes from Sorcery path will make Karthus much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Karthus runes: mid №5 in LoL S11

Harassing enemy with skills

Plus more mana and threat to enemies

Primary path

Sorcery

Arcane Comet

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Arcane Comet together with all the additional runes from Sorcery path will make Karthus much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more


Karthus runes for adc in League of Legends

All the optimal builds for bot lane in LoL

Karthus runes: adc №1 in LoL S11

Continuous damage increase

Plus more mana and threat to enemies

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing bot lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Karthus runes: adc №2 in LoL S11

Continuous damage increase

Plus maximum increase in strength

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Sorcery

Transcendence

Gathering Storm

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing bot lane in season 11 League of Legends.

The secondary path is Sorcery. Transcendence is perfect for champions who need to reduce cooldowns. Gathering Storm will allow you to take up the enemy... read more

Karthus runes: adc №3 in LoL S11

Continuous damage increase

Plus saving in the early game and CDR

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Inspiration

Magical Footwear

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing bot lane in season 11 League of Legends.

The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Cosmic Insight allows you to get... read more

Karthus runes: adc №4 in LoL S11

Abilities and attacks damage

Plus more mana and threat to enemies

Primary path

Sorcery

Summon Aery

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Summon Aery together with all the additional runes from Sorcery path will make Karthus much stronger while playing bot lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Karthus runes: adc №5 in LoL S11

Harassing enemy with skills

Plus more mana and threat to enemies

Primary path

Sorcery

Arcane Comet

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Arcane Comet together with all the additional runes from Sorcery path will make Karthus much stronger while playing bot lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more


Karthus runes for ARAM in League of Legends

All the optimal builds for the ARAM in LoL

Karthus runes: ARAM №1 in LoL S11

Continuous damage increase

Plus more mana and threat to enemies

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing the ARAM in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Karthus runes: ARAM №2 in LoL S11

Continuous damage increase

Plus maximum increase in strength

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Sorcery

Transcendence

Gathering Storm

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing the ARAM in season 11 League of Legends.

The secondary path is Sorcery. Transcendence is perfect for champions who need to reduce cooldowns. Gathering Storm will allow you to take up the enemy... read more

Karthus runes: ARAM №3 in LoL S11

Continuous damage increase

Plus getting a free stopwatch and CDR

Primary path

Domination

Dark Harvest

Cheap Shot

Secondary

Inspiration

Perfect Timing

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Dark Harvest together with all the additional runes from Domination path will make Karthus much stronger while playing the ARAM in season 11 League of Legends.

The secondary path is Inspiration. Perfect Timing is indispensable for champions who need stasis to play combinations, as well as for everyone buying... read more

Karthus runes: ARAM №4 in LoL S11

Harassing enemy with skills

Plus significant CDR of the ultimate

Primary path

Sorcery

Arcane Comet

Manaflow Band

Secondary

Domination

Taste of Blood

Ultimate Hunter

+ 2 others and statistics slots

Read complete description

Arcane Comet together with all the additional runes from Sorcery path will make Karthus much stronger while playing the ARAM in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ultimate Hunter will allow you to use the... read more