The complete list:

Bot lane (view best option)

ARAM 5v5 (view best option)

Runes for Kai'Sa in League of Legends season 10

We present you all the best options available in S10. The runes listed below on the page showed effectiveness for this character in 2020 year, because they can unlock most of his strengths and also neutralize the maximum possible amount of weaknesses.

The list includes all the options that have any value nowadays. This will allow to flexibly adapt to your opponent in the role and team compositions in general when playing the champion Kai'Sa (for example, if you need to be really aggressive).

Please, choose the position you need

Bot lane

ARAM 5v5


Kai'Sa runes for adc in League of Legends

All the optimal builds for bot lane in LoL

Kai'Sa runes: adc №1 in LoL S10

Powerful auto attacks series

Plus mana and increasing vampirism

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  1. Domination
  2. Hail of Blades
  3. Taste of Blood
  4. Eyeball Collection
  5. Ravenous Hunter
  6. Precision
  7. Presence of Mind
  8. Legend: Bloodline
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Hail of Blades together with all the additional runes from Domination path will make Kai'Sa much stronger while playing bot lane in season 10 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Kai'Sa runes: adc №2 in LoL S10

Powerful auto attacks series

Plus maximum increase in strength

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  1. Domination
  2. Hail of Blades
  3. Taste of Blood
  4. Eyeball Collection
  5. Ravenous Hunter
  6. Sorcery
  7. Nimbus Cloak
  8. Gathering Storm
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Hail of Blades together with all the additional runes from Domination path will make Kai'Sa much stronger while playing bot lane in season 10 League of Legends.

The secondary path is Sorcery. Nimbus Cloak will give the champion a good movement speed boost after using a summoner spell. Gathering Storm will allow... read more

Kai'Sa runes: adc №3 in LoL S10

Powerful auto attacks series

Plus saving and enhancing early game

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  1. Domination
  2. Hail of Blades
  3. Taste of Blood
  4. Eyeball Collection
  5. Ravenous Hunter
  6. Inspiration
  7. Magical Footwear
  8. Biscuit Delivery
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Hail of Blades together with all the additional runes from Domination path will make Kai'Sa much stronger while playing bot lane in season 10 League of Legends.

The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Biscuit Delivery will provide... read more

Kai'Sa runes: adc №4 in LoL S10

More damage for aggression

Plus maximum increase in strength

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  1. Precision
  2. Press the Attack
  3. Presence of Mind
  4. Legend: Bloodline
  5. Coup de Grace
  6. Sorcery
  7. Nimbus Cloak
  8. Gathering Storm
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Press the Attack together with all the additional runes from Precision path will make Kai'Sa much stronger while playing bot lane in season 10 League of Legends.

The secondary path is Sorcery. Nimbus Cloak will give the champion a good movement speed boost after using a summoner spell. Gathering Storm will allow... read more

Kai'Sa runes: adc №5 in LoL S10

More damage for aggression

Plus saving and enhancing early game

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  1. Precision
  2. Press the Attack
  3. Presence of Mind
  4. Legend: Bloodline
  5. Coup de Grace
  6. Inspiration
  7. Magical Footwear
  8. Biscuit Delivery
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Press the Attack together with all the additional runes from Precision path will make Kai'Sa much stronger while playing bot lane in season 10 League of Legends.

The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Biscuit Delivery will provide... read more

Kai'Sa runes: adc №6 in LoL S10

More damage for aggression

Plus restoration of health in the fight

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  1. Precision
  2. Press the Attack
  3. Presence of Mind
  4. Legend: Bloodline
  5. Coup de Grace
  6. Domination
  7. Taste of Blood
  8. Ravenous Hunter
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Press the Attack together with all the additional runes from Precision path will make Kai'Sa much stronger while playing bot lane in season 10 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Kai'Sa runes: adc №7 in LoL S10

Increasing the attack speed

Plus maximum increase in strength

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  1. Precision
  2. Lethal Tempo
  3. Presence of Mind
  4. Legend: Bloodline
  5. Coup de Grace
  6. Sorcery
  7. Nimbus Cloak
  8. Gathering Storm
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Lethal Tempo together with all the additional runes from Precision path will make Kai'Sa much stronger while playing bot lane in season 10 League of Legends.

The secondary path is Sorcery. Nimbus Cloak will give the champion a good movement speed boost after using a summoner spell. Gathering Storm will allow... read more

Kai'Sa runes: adc №8 in LoL S10

Lots of healing for champion

Plus maximum increase in strength

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  1. Precision
  2. Fleet Footwork
  3. Presence of Mind
  4. Legend: Bloodline
  5. Coup de Grace
  6. Sorcery
  7. Nimbus Cloak
  8. Gathering Storm
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Fleet Footwork together with all the additional runes from Precision path will make Kai'Sa much stronger while playing bot lane in season 10 League of Legends.

The secondary path is Sorcery. Nimbus Cloak will give the champion a good movement speed boost after using a summoner spell. Gathering Storm will allow... read more


Kai'Sa runes for ARAM in League of Legends

All the optimal builds for the ARAM in LoL

Kai'Sa runes: ARAM №1 in LoL S10

Continuous damage increase

Plus more mana and threat to enemies

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  1. Domination
  2. Dark Harvest
  3. Taste of Blood
  4. Eyeball Collection
  5. Ravenous Hunter
  6. Precision
  7. Presence of Mind
  8. Coup de Grace
  9. 9 adaptive force
  10. 9 adaptive force
  11. 6 armor

Dark Harvest together with all the additional runes from Domination path will make Kai'Sa much stronger while playing the ARAM in season 10 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Kai'Sa runes: ARAM №2 in LoL S10

Continuous damage increase

Plus more mana and increased CDR

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  1. Domination
  2. Dark Harvest
  3. Taste of Blood
  4. Eyeball Collection
  5. Ravenous Hunter
  6. Sorcery
  7. Manaflow Band
  8. Transcendence
  9. 9 adaptive force
  10. 9 adaptive force
  11. 6 armor

Dark Harvest together with all the additional runes from Domination path will make Kai'Sa much stronger while playing the ARAM in season 10 League of Legends.

The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more

Kai'Sa runes: ARAM №3 in LoL S10

Powerful auto attacks series

Plus mana and increasing vampirism

Read complete description

  1. Domination
  2. Hail of Blades
  3. Taste of Blood
  4. Eyeball Collection
  5. Ravenous Hunter
  6. Precision
  7. Presence of Mind
  8. Legend: Bloodline
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Hail of Blades together with all the additional runes from Domination path will make Kai'Sa much stronger while playing the ARAM in season 10 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Kai'Sa runes: ARAM №4 in LoL S10

More damage for aggression

Plus maximum increase in strength

Read complete description

  1. Precision
  2. Press the Attack
  3. Presence of Mind
  4. Legend: Bloodline
  5. Coup de Grace
  6. Sorcery
  7. Nimbus Cloak
  8. Gathering Storm
  9. 10% attack speed
  10. 9 adaptive force
  11. 6 armor

Press the Attack together with all the additional runes from Precision path will make Kai'Sa much stronger while playing the ARAM in season 10 League of Legends.

The secondary path is Sorcery. Nimbus Cloak will give the champion a good movement speed boost after using a summoner spell. Gathering Storm will allow... read more