The complete list:

Mid lane

Top lane

Bot lane

ARAM 5v5

Runes for Cassiopeia in League of Legends season 11

We present you all the best options available in S11. The runes listed below on the page showed effectiveness for this character in 2021 year, because they can unlock most of his strengths and also neutralize the maximum possible amount of weaknesses.

The list includes all the options that have any value nowadays. This will allow to flexibly adapt to your opponent in the role and team compositions in general when playing the champion Cassiopeia (for example, if you need to be really aggressive).

Please, choose the position you need

Mid lane

Top lane

Bot lane

ARAM 5v5


Cassiopeia runes for mid in League of Legends

All the optimal builds for mid lane in LoL

Cassiopeia runes: mid №1 in LoL S11

Damage and lots of healing

Plus restoration of health in the fight

Primary path

Precision

Conqueror

Presence of Mind

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Cassiopeia much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Cassiopeia runes: mid №2 in LoL S11

Damage and lots of healing

Plus more mana and increased CDR

Primary path

Precision

Conqueror

Presence of Mind

Secondary

Sorcery

Manaflow Band

Transcendence

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Cassiopeia much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more

Cassiopeia runes: mid №3 in LoL S11

Impressive amount of mobility

Plus restoration of health in the fight

Primary path

Sorcery

Phase Rush

Manaflow Band

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Cassiopeia runes: mid №4 in LoL S11

Impressive amount of mobility

Plus more mana and threat to enemies

Primary path

Sorcery

Phase Rush

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more

Cassiopeia runes: mid №5 in LoL S11

Impressive amount of mobility

Plus resource recovery and CDR

Primary path

Sorcery

Phase Rush

Manaflow Band

Secondary

Inspiration

Biscuit Delivery

Cosmic Insight

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Inspiration. Biscuit Delivery will provide health and mana on the lane, as well as increase the maximum amount of the latter. Cosmic... read more

Cassiopeia runes: mid №6 in LoL S11

Harassing enemy with skills

Plus restoration of health in the fight

Primary path

Sorcery

Arcane Comet

Manaflow Band

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Arcane Comet together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Cassiopeia runes: mid №7 in LoL S11

The maximum burst damage

Plus more mana and threat to enemies

Primary path

Domination

Electrocute

Taste of Blood

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Electrocute together with all the additional runes from Domination path will make Cassiopeia much stronger while playing mid lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more


Cassiopeia runes for top in League of Legends

All the optimal builds for top lane in LoL

Cassiopeia runes: top №1 in LoL S11

Damage and lots of healing

Plus restoration of health in the fight

Primary path

Precision

Conqueror

Presence of Mind

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Cassiopeia much stronger while playing top lane in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Cassiopeia runes: top №2 in LoL S11

Damage and lots of healing

Plus more mana and increased CDR

Primary path

Precision

Conqueror

Presence of Mind

Secondary

Sorcery

Manaflow Band

Transcendence

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Cassiopeia much stronger while playing top lane in season 11 League of Legends.

The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more

Cassiopeia runes: top №3 in LoL S11

Impressive amount of mobility

Plus restoration of health in the fight

Primary path

Sorcery

Phase Rush

Manaflow Band

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing top lane in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Cassiopeia runes: top №4 in LoL S11

Impressive amount of mobility

Plus more mana and threat to enemies

Primary path

Sorcery

Phase Rush

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing top lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more


Cassiopeia runes for adc in League of Legends

All the optimal builds for bot lane in LoL

Cassiopeia runes: adc №1 in LoL S11

Damage and lots of healing

Plus restoration of health in the fight

Primary path

Precision

Conqueror

Presence of Mind

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Cassiopeia much stronger while playing bot lane in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Cassiopeia runes: adc №2 in LoL S11

Damage and lots of healing

Plus more mana and increased CDR

Primary path

Precision

Conqueror

Presence of Mind

Secondary

Sorcery

Manaflow Band

Transcendence

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Cassiopeia much stronger while playing bot lane in season 11 League of Legends.

The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more

Cassiopeia runes: adc №3 in LoL S11

Impressive amount of mobility

Plus restoration of health in the fight

Primary path

Sorcery

Phase Rush

Manaflow Band

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing bot lane in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Cassiopeia runes: adc №4 in LoL S11

Impressive amount of mobility

Plus more mana and threat to enemies

Primary path

Sorcery

Phase Rush

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing bot lane in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more


Cassiopeia runes for ARAM in League of Legends

All the optimal builds for the ARAM in LoL

Cassiopeia runes: ARAM №1 in LoL S11

Damage and lots of healing

Plus restoration of health in the fight

Primary path

Precision

Conqueror

Presence of Mind

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Cassiopeia much stronger while playing the ARAM in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Cassiopeia runes: ARAM №2 in LoL S11

Damage and lots of healing

Plus maximum increase in strength

Primary path

Precision

Conqueror

Presence of Mind

Secondary

Sorcery

Manaflow Band

Gathering Storm

+ 2 others and statistics slots

Read complete description

Conqueror together with all the additional runes from Precision path will make Cassiopeia much stronger while playing the ARAM in season 11 League of Legends.

The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more

Cassiopeia runes: ARAM №3 in LoL S11

Impressive amount of mobility

Plus restoration of health in the fight

Primary path

Sorcery

Phase Rush

Manaflow Band

Secondary

Domination

Taste of Blood

Ravenous Hunter

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing the ARAM in season 11 League of Legends.

The secondary path is Domination. Taste of Blood is a great way to maintain a high amount of health on the lane. Ravenous Hunter is an excellent source of... read more

Cassiopeia runes: ARAM №4 in LoL S11

Impressive amount of mobility

Plus more mana and threat to enemies

Primary path

Sorcery

Phase Rush

Manaflow Band

Secondary

Precision

Presence of Mind

Coup de Grace

+ 2 others and statistics slots

Read complete description

Phase Rush together with all the additional runes from Sorcery path will make Cassiopeia much stronger while playing the ARAM in season 11 League of Legends.

The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more