We present you all the best options available in S10. The runes listed below on the page showed effectiveness for this character in 2020 year, because they can unlock most of his strengths and also neutralize the maximum possible amount of weaknesses.
The list includes all the options that have any value nowadays. This will allow to flexibly adapt to your opponent in the role and team compositions in general when playing the champion Anivia (for example, if you need to be really aggressive).
All the optimal builds for mid lane in LoL
Plus more mana and threat to enemies
Primary path
Domination
Electrocute
Cheap Shot
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionElectrocute together with all the additional runes from Domination path will make Anivia much stronger while playing mid lane in season 10 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus maximum increase in strength
Primary path
Domination
Electrocute
Cheap Shot
Secondary
Sorcery
Manaflow Band
Gathering Storm
+ 2 others and statistics slots
Read complete descriptionElectrocute together with all the additional runes from Domination path will make Anivia much stronger while playing mid lane in season 10 League of Legends.
The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more
Plus more mana and threat to enemies
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing mid lane in season 10 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus saving and enhancing early game
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Inspiration
Magical Footwear
Biscuit Delivery
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing mid lane in season 10 League of Legends.
The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Biscuit Delivery will provide... read more
Plus power in battle and speed on the map
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Domination
Cheap Shot
Relentless Hunter
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing mid lane in season 10 League of Legends.
The secondary path is Domination. Cheap Shot will serve as a constant source of additional damage to enemies after applying any control to them... read more
All the optimal builds for support in LoL
Plus more mana and threat to enemies
Primary path
Domination
Electrocute
Cheap Shot
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionElectrocute together with all the additional runes from Domination path will make Anivia much stronger while playing support in season 10 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus increased mana and abilities damage
Primary path
Domination
Electrocute
Cheap Shot
Secondary
Sorcery
Manaflow Band
Scorch
+ 2 others and statistics slots
Read complete descriptionElectrocute together with all the additional runes from Domination path will make Anivia much stronger while playing support in season 10 League of Legends.
The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more
Plus saving and enhancing early game
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Inspiration
Magical Footwear
Biscuit Delivery
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing support in season 10 League of Legends.
The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Biscuit Delivery will provide... read more
Plus more mana and threat to enemies
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing support in season 10 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus power in battle and speed on the map
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Domination
Cheap Shot
Relentless Hunter
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing support in season 10 League of Legends.
The secondary path is Domination. Cheap Shot will serve as a constant source of additional damage to enemies after applying any control to them... read more
All the optimal builds for top lane in LoL
Plus more mana and threat to enemies
Primary path
Domination
Electrocute
Cheap Shot
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionElectrocute together with all the additional runes from Domination path will make Anivia much stronger while playing top lane in season 10 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus maximum increase in strength
Primary path
Domination
Electrocute
Cheap Shot
Secondary
Sorcery
Manaflow Band
Gathering Storm
+ 2 others and statistics slots
Read complete descriptionElectrocute together with all the additional runes from Domination path will make Anivia much stronger while playing top lane in season 10 League of Legends.
The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more
Plus saving and enhancing early game
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Inspiration
Magical Footwear
Biscuit Delivery
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing top lane in season 10 League of Legends.
The secondary path is Inspiration. Magical Footwear are a good source of cost savings, and even give a little more speed. Biscuit Delivery will provide... read more
Plus more mana and threat to enemies
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing top lane in season 10 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus power in battle and speed on the map
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Domination
Cheap Shot
Relentless Hunter
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing top lane in season 10 League of Legends.
The secondary path is Domination. Cheap Shot will serve as a constant source of additional damage to enemies after applying any control to them... read more
All the optimal builds for the ARAM in LoL
Plus more mana and threat to enemies
Primary path
Domination
Dark Harvest
Cheap Shot
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionDark Harvest together with all the additional runes from Domination path will make Anivia much stronger while playing the ARAM in season 10 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus more mana and increased CDR
Primary path
Domination
Dark Harvest
Cheap Shot
Secondary
Sorcery
Manaflow Band
Transcendence
+ 2 others and statistics slots
Read complete descriptionDark Harvest together with all the additional runes from Domination path will make Anivia much stronger while playing the ARAM in season 10 League of Legends.
The secondary path is Sorcery. Manaflow Band will allow you to experience less problems with this resource through an increase in its amount and... read more
Plus more mana and threat to enemies
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Precision
Presence of Mind
Coup de Grace
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing the ARAM in season 10 League of Legends.
The secondary path is Precision. Presence of Mind will restore part of the mana or energy when participating in the killing of the champion, as well as... read more
Plus true damage and ability vampirism
Primary path
Sorcery
Arcane Comet
Manaflow Band
Secondary
Domination
Cheap Shot
Ravenous Hunter
+ 2 others and statistics slots
Read complete descriptionArcane Comet together with all the additional runes from Sorcery path will make Anivia much stronger while playing the ARAM in season 10 League of Legends.
The secondary path is Domination. Cheap Shot will serve as a constant source of additional damage to enemies after applying any control to them. Ravenous... read more